Hay fever season in Japan can be quite challenging, but there are several hay fever medicines in Japan available to help relieve symptoms. From eye drops to pollen-blocking sprays, these products are designed to reduce discomfort caused by allergens like pollen, dust, and PM2.5. In this article, we will explore some representative hay fever medicines in Japan, focusing on solutions to protect the eyes, face, and hair from allergens during allergy season.
For the 2025 peak forecast by region, please see the following article.
Table of Contents
Chapter 1: Allergy Medicines
1. Alesion 20
Alesion 20 is an allergy medication that contains 20 mg of epinastine hydrochloride per tablet, a second-generation antihistamine. It is highly effective in relieving sneezing and a runny nose. As a second-generation antihistamine, it is less likely to cause drowsiness compared to first-generation allergy medications.
Ingredients
In addition to the active ingredient, Alesion 20 contains the following inactive ingredients:
- Silicon dioxide
- Lactose
- Hypromellose
- Povidone
- Ethyl acrylate-methyl methacrylate copolymer
- Macrogol
- Silicone resin
- Magnesium stearate
- Talc
- Titanium dioxide
- Corn starch
If you have any concerns about allergies or interactions with other medicines, consult a pharmacist before use.
Effectiveness
Alesion 20 helps relieve allergy symptoms caused by pollen, house dust, and other airborne allergens. It is effective for:
- Runny nose
- Nasal congestion
- Sneezing
Dosage and Usage
Take the following dose once a day before bedtime with water or lukewarm water:
- Adults (15 years and older): 1 tablet
- Children under 15: Do not use
2. Allegra FX
Allegra FX is a second-generation antihistamine that effectively relieves allergy symptoms such as sneezing, runny nose, and nasal congestion caused by pollen and house dust. It is less likely to cause drowsiness since it does not affect the brain as much, making it an ideal allergy medicine for nasal issues.
Ingredients
In addition to the active ingredient, Allegra FX contains:
- Crystalline cellulose
- Partially hydrolyzed starch
- Crosscarmellose sodium
- Magnesium stearate
- Light anhydrous silica
- Hypromellose
- Povidone
- Titanium dioxide
- Macrogol 400
- Ferric oxide (red and yellow)
Effectiveness
Allegra FX helps relieve allergy symptoms caused by pollen, house dust, and other airborne allergens. It is effective for:
- Sneezing
- Runny nose
- Nasal congestion
Dosage and Usage
Take 1 tablet twice a day (morning and evening) with water:
- Adults (15 years and older): 1 tablet per dose, 2 times a day
- Children under 15: Do not use
Chapter 2: Allergy Eye Drops
1. Mightyia Arpitatt EXα7
Mightyia Arpitatt EXα7 is an allergy-specific eye drop containing the most active ingredients in the Arpitatt series—seven active ingredients. This eye drop is designed to address the mechanism behind allergy symptoms. Three of its key ingredients target inflammation caused by allergens such as pollen and house dust, providing quick relief for symptoms like eye itching, foreign body sensation (a feeling of something in the eye), and redness. Additionally, it contains ingredients that protect and help repair the cornea.
Ingredients
Each 1 ml of solution contains the following ingredients:
- Sodium cromoglycate – 10 mg
- Chlorpheniramine maleate – 0.3 mg
- Pranoprofen – 0.5 mg
- Chondroitin sulfate ester sodium – 5 mg
- Taurine – 1 mg
- L-asparagine potassium – 2 mg
- D-alpha-tocopherol acetate – 0.1 mg
Inactive ingredients:
- Boric acid
- Borax
- Dibutylhydroxytoluene
- Polysorbate 80
- Benzalkonium chloride
- L-menthol
- pH adjusters
Effectiveness
Mightyia Arpitatt EXα7 helps to relieve the following eye allergy symptoms caused by pollen, house dust, and other airborne allergens:
- Redness
- Itching
- Blurred vision (e.g., when there is an excess of eye discharge)
- Watery eyes
- Foreign body sensation (the feeling of something in the eye)
Dosage and Usage
- Dosage: Apply 1-2 drops in each eye, 4 times a day.
- Important Note: Always follow the recommended dosage. If symptoms persist, consult a healthcare professional.
2. Rohto Allguard Cool EX
Rohto Allguard Cool EX is an eye drop that provides effective relief for eye irritation caused by allergens like pollen. It contains four active ingredients that work to reduce inflammation and relieve itching, providing quick comfort for your eyes.
Ingredients
Active Ingredients:
- Sodium azulenesulfonate hydrate (water-soluble azulene) – 0.02%
Derived from a medicinal herb, it reduces inflammation and relieves itching and congestion. The purple color of the liquid comes from the natural color of this ingredient. - Chlorpheniramine maleate – 0.03%
Blocks histamine (the substance responsible for allergy symptoms), relieving itching. - Tetrahydrozoline hydrochloride – 0.02%
Constricts blood vessels to relieve redness. - Vitamin B6 – 0.1%
Supplies nutrients to the eyes and promotes cell metabolism.
- Sodium azulenesulfonate hydrate (water-soluble azulene) – 0.02%
Inactive Ingredients:
- Boric acid, borax, isotonic agents, alginic acid, L-menthol, D-camphor, peppermint oil, propylene glycol, polysorbate 80, pH adjusters.
Effectiveness
Rohto Allguard Cool EX is designed to relieve the following symptoms:
- Itching of the eyes
- Conjunctival congestion (redness of the eyes)
- Blepharitis (inflammation of the eyelids)
- Blurred vision (especially when there is excess discharge)
- Prevention of eye diseases (such as after swimming or exposure to dust and sweat)
- Eye inflammation caused by UV rays or other light exposure (e.g., snow blindness)
- Eye fatigue
- Discomfort from wearing hard contact lenses
Dosage and Usage
- Dosage: Apply 1-2 drops into each eye, 3-6 times a day.
- Important Note: Always follow the recommended dosage. If symptoms persist, consult a healthcare professional.
3. Eye Bon AL
Eye Bon AL is designed to wash away foreign particles like pollen and dust from the eyes, which can cause allergic reactions such as itching and inflammation due to histamine secretion. This product contains an antihistamine ingredient to help alleviate discomfort caused by allergens.
Ingredients
Active Ingredients (per 100 mL):
- Epsilon-Aminocaproic Acid: 300 mg – Anti-inflammatory
- Dipotassium Glycyrrhizinate: 25 mg – Anti-inflammatory
- Chlorpheniramine Maleate: 3 mg – Antihistamine
- Chondroitin Sulfate Ester Sodium: 10 mg – Corneal protection
Additives:
- Boric acid, borax, Polysorbate 80, EDTA-Na, L-menthol, D-borneol, pH adjuster
Effectiveness
- Eye cleaning
- Prevention of eye diseases (after swimming or when dust and sweat get into the eyes)
Dosage and Usage
- Use 5 mL to rinse eyes 3-6 times per day.
- Fill the provided cup with the solution and wash the eyes thoroughly.

Chapter 3: Pollen Protection Sprays
There are also spray types that prevent pollen from sticking to the face and hair.
1.Ihada Allen Screen EX Spray Type
This spray can be used over makeup and protects the face and hair from pollen, viruses, and PM2.5. It features a natural hot spring water formula and utilizes Shiseido’s patented technology to create an ionic transparent veil that suppresses the adhesion of pollen and other particles.
Ingredients
- Water
- Ethanol
- Polyquaternium-51
- PEG/PPG-14/7 Dimethyl Ether
- Nitrogen
- Sodium Citrate
- PEG-30 Phytosterol
- Citric Acid
- Hot Spring Water
- Dysteryldimonium Chloride
- Isostearylal Alcohol
- Mineral Oil
- Isopropanol
- Phenoxyethanol
Effectiveness
- Shiseido’s Patented “Particulate Adsorption Technology”
- Blocks pollen and PM2.5
- Allergy Screen EX also blocks viruses
Dosage and Usage
- Use 3 to 5 times a day, every 4 hours.
2. Allen Block Earth Pharmaceutical Pollen Guard Moist Veil
This pollen guard keeps the body clean and prevents the uncomfortable feeling of static cling. It repels harmful substances like pollen, viruses, PM2.5, and house dust by preventing static electricity.
Ingredients
- Hydroxypropyl Chitosan
- Sodium Hyaluronic Acid
- Glucocylceramide
- Placenta
- Argan Oil
- Odor Tensiquaoi Water (Natural Rose Geranium Water)
- Methylparaben
- Ethanol
Effectiveness
- Spray prevents the adhesion of pollen, viruses, PM2.5, and house dust.
Dosage and Usage
- Use once a day.
- Close your eyes and mouth, then spray from a distance of about 20 cm, applying an appropriate amount (around 3 seconds) to the face and hair.
In Japan, a variety of hay fever medicines are available to help manage symptoms and provide relief during allergy season. Whether you’re using eye drops or pollen-blocking sprays, these products can effectively protect against common allergens. However, it’s important to always check the instructions carefully and confirm the dosage before purchasing any product. For more detailed information, please consult a pharmacist to ensure you’re selecting the right medicine for your needs.